Many families are returning home from the long holiday weekend to head back to work.
Missouri State Highway Patrol is advising everyone to have a plan in place before hitting the roads.
Sgt. Eric Brown with Troop B stated one issue they notice after a holiday is fatigued driving, which can be just as dangerous as driving impaired.
"If they are not well-rested, share that job of driving. You should take a break, stop and get out and get something to drink and eat, stretch your legs, and get refreshed before you drive again," Brown said.
He said the key is to make a list, take your time, and make sure safety is your top priority.
"Obey the traffic laws, be a safe and courteous driver. You also should be well-rested," Brown said.
"After a long weekend of celebrating and spending time with family, boating, whatever it may be, they are often fatigued on the way home. We often see the same thing from a fatigued driver as we do an impaired driver."
Troopers will continue enforcing the Operation "CARE" campaign, which means crash awareness reduction effort.
That includes speeding, seat belt usage, drunk driving, and other traffic violations.
On Friday, MSHP said 32 people were arrested for driving under the influence.
Troopers arrested 32 people yesterday for #DWI. If alcohol is a part of your plans during this #MemorialDayWeekend please designate a sober driver. Troopers are often blamed for ruining a drunk drivers life by arresting them. The fault lies all with the driver who CHOSE to drive. pic.twitter.com/T9egqoBnBP— MSHP Troop B (@MSHPTrooperB) May 23, 2020